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Cummins QSF4.5, ISF4.5 Fuel Injector 2021-2024: OEM 5364543 ( Set of 6 )

CUMMINS QSF4.5, ISF4.5 FUEL INJECTOR 2021-2024: OEM 5364543 ( SET OF 6 )

Shipping ICON

ORDERS PLACED BEFORE 3PM EST WILL SHIP SAME DAY

WARRANTY ICON

WARRANTY
1M MILES OR 1 YEAR

$2,099.70

CORE CHARGE:

$800.00
iCORE DISCLAIMER: The CORE charge is a 30 day hold and will not be processed as long as the CORE is returned within 30 days. If you do not have a CORE or fail to return the CORE within 30 days, the CORE charge hold amount will be processed at that time.

AVAILABILITY IN STOCK
OEM NUMBER5364543
PART TYPEFuel Injector
BRANDTamerx Diesel Products
ENGINE MAKECummins
ENGINE TYPEQSF4.5, ISF4.5
YEAR2021-2024
PART NUMBER5364543RM-SET

PRODUCT DESCRIPTION

This is a Remanufactured Tamerx Fuel Injector, Tamerx part number 5364543RM-SET ( OEM Part Number 5364543 ). All parts are proudly remanufactured in the U.S.A. to the highest of OEM standards, and improvements are often applied to the original design in the remanufacturing process. This part is primarily made for a Cummins QSF4.5, ISF4.5, production years 2021-2024, and comes with a One Million Miles or One Year Warranty. For additional warranty info Click Here

OEM NUMBERS

Primary OEM5364543
Additional OEM5364543

ADDITIONAL DETAILS

CONDITIONRemanufactured
UPC / Barcode00840490537965
WEIGHT6.00 LBS

SHIPPING OPTIONS

Ship Weight : 6.00 LBS
UPS Ground, 2nd Day Air, Next Day Air

SHIPPING POLICY

Tamerx Diesel Products ships via UPS Ground. Next day air shipping can be arranged for a reasonable price of anywhere from $50.00 - $100.00 depending on the weight of the product and your location. We will do everything we can to make sure that you get the service you need. We understand how important it is to receive your order as quickly as possible.
In most cases Tamerx Diesel Products only needs one address, as long as your product is shipping to the same location as your billing information. In order to eliminate credit card fraud, your billing information must match the credit card you provide.

The terms, conditions, and details of our warranty vary from product to product. Specific warranty details can be found below.

Tamerx Diesel Products provides a replacement warranty on all of our parts. The duration and mileage limitations of the warranty vary by product and are specified on the product's detail page/item listing.

Please note that the warranty covers replacement of the part and the cost of shipping the replacement part to you only. It does not cover any shop, labor, towing, or any similar or related costs. This is not a "money back guarantee".

If you experience a problem with your part or it is not functioning properly, the correct warranty procedure is to call us at (510) 257-1777 (8:00 AM - 5:00 PM ET Monday through Friday). Be sure to have your order number and/or other relevant order information ready so we can easily locate your order and resolve your issue as quickly as possible. From that point, we will review with you any troubleshooting steps that may need to be taken and other areas or systems that can be checked to rule out external problems contributing to your part's issue. If a replacement is determined to be necessary, we will then arrange for your replacement part to ship out ASAP and issue any necessary return shipping labels and/or documents.

As is the case for the majority of the diesel products sold on Tamerx Diesel Products, your part's warranty is active as soon as you install it. In some other cases, warranty activation is contingent upon you sending us your core (i.e., your old part). Tamerx Diesel Products will provide you a return shipping label for parts that have a warranty with a core return condition. When we have received your core return, the part's warranty coverage begins. We reserve the right to void the product warranty if your core is not received within the allotted time, or if it isn't received at all. If the warranty for the diesel part you are purchasing has a core return requirement, it will be clearly noted on the product detail page/item listing.

What is a Core Charge?

A core charge (also called "core deposit") is similar to the deposit you might pay for a can or bottle of soda and is a standard requirement in the auto parts industry. For example, in many states, to promote recycling, you pay a deposit when you purchase a can of soda and receive your deposit back when you return the empty can. Many automotive parts have a core charge, or core price, that works in essentially the same way as a soda can deposit.

30 Day Core Charge Hold

You authorize Tamerx Diesel Products, to hold your credit card for the specified core charge amount and that you agree to return your core with 30 days of receiving the purchased part. When we have received your core return, the hold is released and the core charge payment is canceled.

The customer, or parts buyer, is responsible for any shipping costs associated with core returns unless otherwise specified in the product listing/detail page. Tamerx Diesel Products offers prepaid UPS shipping labels (SKU numbers UPS-CR1 and UPS-CR2) for use in returning your core that are available for purchase on our website during your shopping/order process.

The shipping label you will need to use for the core return is dependent upon what part you are purchasing. UPS-CR1 is good for cores weighing up to 20 pounds. UPS-CR2 is appropriate for shipping cores weighing 21 pounds or more. You must include enough information with the core return that clearly identifies it as a.) a Core Return, and b.) contains enough information we can use to clearly associate the core return with your order. Including a copy of the invoice or packing slip that came with the original shipment, clearly marked "Core Return", is ideal. Alternately, you can include a note marked as "Core Return" that includes your order number, full name and address, and phone number or other contact information. Failure to include this information with your returned core will most likely delay any due core credit being issued and/or delay any applicable warranty activation. Core returns need to be for the exact part purchased and cannot be damaged. Substituting another part in place of the part you have purchased is not acceptable.

All fluids must be drained.

If you have purchased a set or a parts package, you will need to return cores for all components of the set. For example, if you have purchaed a high pressure oil pump with an IPR valve, you will need to return both HPOP and IPR valve cores to receive proper credit. If you have purchased an EGR cooler/EGR valve package, your core return must consist of an EGR cooler core and an EGR valve core, or core credit will not be given.

Core Charges are often mandated by state legislature, and, as such, the actual core charge and taxes on the charge may vary depending on the state in which you buy your part. The Tamerx Diesel Products core charge presented to you online today with your item is representative of the most common core charge.


Available as a complete set of six, the OEM 5364543 Fuel Injectors are designed for 2021–2024 Cummins QSF4.5 and ISF4.5 engine applications and manufactured to meet original equipment specifications. Each injector is engineered to deliver precise fuel metering and accurate atomization within high-pressure common rail systems. Constructed with durable internal components, these injectors are built to withstand the rigorous demands of commercial and industrial diesel environments. Replacing injectors as a matched set helps maintain balanced fuel distribution across all cylinders for consistent combustion. Tamerx Diesel Products LLC supplies this set of six Cummins fuel injectors as a dependable solution for maintaining reliable fuel system operation.

FITMENT CHART

YEARMAKEENGINE(S)
2021Cummins QSF4.5 ISF4.5
2022Cummins QSF4.5 ISF4.5
2023Cummins QSF4.5 ISF4.5
2024Cummins QSF4.5 ISF4.5

PEOPLE ALSO ASKS | BLOG(S)

Balanced fuel delivery is essential in Cummins QSF4.5 and ISF4.5 diesel engines. The OEM 5364543 Fuel Injector Set of 6 is important because it ensures each cylinder receives precise and consistent fuel flow, supporting smooth engine operation in 2021–2024 applications.

Since these engines are inline four-cylinder platforms, replacing injectors as a matched set helps maintain uniform combustion across all cylinders. Even small variations in injector flow rates can lead to rough idle, uneven combustion, increased emissions, and reduced efficiency.

The Cummins OEM 5364543 injector set plays a critical role by:

  • Delivering accurate fuel metering to each cylinder
  • Maintaining consistent spray patterns
  • Supporting proper air-to-fuel ratios
  • Reducing the risk of cylinder imbalance
  • Working seamlessly with the engine control module (ECM)

Modern diesel engines rely on electronically controlled injection systems. Each injector responds to signals from the ECM, adjusting fuel delivery based on load, temperature, and operating conditions. When all injectors function evenly, the engine operates more smoothly and reliably.

Installing a complete set of six ensures matched calibration and balanced performance across the system. This helps prevent uneven wear, misfires, or fuel system-related fault codes.

For fleet operators and equipment owners, the Cummins QSF4.5 and ISF4.5 Fuel Injector OEM 5364543 (Set of 6) is essential for maintaining dependable combustion, stable engine operation, and long-term reliability.

A failing fuel injector can quickly affect how your engine runs. Because injectors control precise fuel delivery, even a small issue can lead to rough operation or poor combustion.

The first step is identifying the symptoms.

Common warning signs include:

  • Rough idle or shaking
  • Engine misfires
  • Hard starting
  • Strong fuel odor
  • Excessive exhaust smoke
  • Decreased fuel efficiency
  • Check engine light

If you notice these issues, avoid ignoring them. Continuing to drive with a faulty injector can cause additional engine damage, especially if fuel is leaking into a cylinder.

Next, have the vehicle professionally diagnosed. A technician may perform:

  • Injector balance testing
  • Fuel pressure checks
  • Scan tool diagnostics
  • Visual inspection for leaks

In some cases, clogged injectors can be cleaned if the problem is caught early. However, if the injector is leaking, electrically damaged, or severely restricted, replacement is usually required.

It’s also important to address the root cause. Contaminated fuel, a failing fuel filter, or water in the system can contribute to injector problems.

Acting quickly helps prevent damage to pistons, valves, and the fuel system while restoring smooth engine operation.

All six injectors are installed into the cylinder head to feed fuel into each combustion chamber.

Yes, the six 5364543 injectors are designed to work with factory fuel rails and electrical connections.

The six injectors in this set are engineered to operate with the diesel fuel specified for these Cummins engines.

A matched set of six 5364543 injectors promotes even fuel delivery and combustion consistency across all cylinders.

Cummins Fuel Injectors